Table 3.
Determination of effective minimum oral therapeutic dose of Ocimum gratissimum methanol leaf extract in rat model of type-2 diabetes.
| OG Extract Dose (mg/kg bw) | Blood Glucose Level (mg/dL) | |||
|---|---|---|---|---|
| 0 h | 1 h | 2 h | 4 h | |
| G100 | 261.4 ± 12.4 | 247.8 ± 14.3 (5.1) | 241.7 ± 11. 8 (6.3) | 237.2 ± 9.1 (9.3) |
| G150 | 284.1 ± 15.8 | 270.6 ± 9.4 (4.8) | 259.5 ± 8.5 (8.7) | 249.3 ± 3.6 (12.3) |
| G200 | 273.7 ± 20.6 | 243.4 ± 14.5 (11.1) | 237.2 ± 14.3 (13.3) | 216.6 ± 17.1 (20.9) |
| G250 | 291.3 ± 14.9 | 260.5 ± 22.2 (10.6) | 241.4 ± 15.8 (17.1) | 206.1 ± 20.5 (29.3) |
| DC | 286.9 ± 15.5 | 282.3 ± 15.1 (1.6) | 277.7 ± 12.2 (3.2) | 274.2 ± 12.3 (4.4) |
Figure in brackets is percentage reduction in blood glucose as compared to Values obtained at 0 h. Data are presented as mean ± SD of 3 animals per group. DC: Diabetic control group without treatment. OG: Ocimum gratissimum.