Table 4.
Groups | FBS (mg/dL) Day 0 | Percentage Decrease after Treatment (%) | |||
---|---|---|---|---|---|
Day 7 | Day 14 | Day 21 | Day 28 | ||
NC | 83.7 ± 5.9 a | 2.4 ± 6.1 b,1 | 1.6 ± 7.0 b,1 | −0.9 ± 5.6 b,1 | 0.6 ± 5.6 b,1 |
DC | 303.3 ± 15.7 b | −22.3 ± 7.0 a,3 | −40.6 ± 8.0 a,1,2 | −44.6 ± 13.0 a,1,2 | −50.5 ± 11.5 a,1 |
OGh | 347.9 ± 7.9 c,d | 10.8 ± 4.4 b,c,1 | 17.8 ± 3.9 c, 1,2 | 20.3 ± 3.8 c,2 | 30.6 ± 5.0 c,3 |
OGc | 365.4 ± 14.6 d | 21.8 ± 3.0 d,1 | 30.6 ± 7.5 d,e,1,2 | 40.6 ± 6.4 d,2 | 54.7 ± 6.6 e,3 |
OGe | 313.2 ± 21.1 b | 12.8 ± 9.4 c,1 | 20.4 ± 9.9 c,d,1,2 | 25.6 ± 8.9 c,1,2 | 32.6 ±5.10 c,2 |
OGb | 389.2 ± 10.2 e | 13.6 ± 5.3 c,d,1 | 37.9 ± 7.9 e,2 | 49.7 ± 7.3 d,2 | 63.5 ± 4.8 f,3 |
OGa | 339.0 ± 8.0 c | 17.9 ± 4.0 c,d,1 | 19.9 ± 4.0 c,1 | 29.0 ± 3.6 c,2 | 44.4 ± 10.9 d,3 |
PC | 421.2 ± 38.2 f | 10.1 ± 11.5 b,c,1 | 26.7 ± 14.1 d,1,2 | 49.1 ± 7. 8 e,2 | 71.7 ± 2.2 f,3 |
Data are presented as mean ± SD of 6 animals per group. Values with different superscript down the column and different alphabet across the column indicate significant difference (p < 0.05). NC: Normal control; DC: Diabetic control; PC: Positive control (Metformin 500 mg/kg bw); OGh: Ocimum gratissimum n-hexane fraction; OGc: Ocimum gratissimum chloroform fraction; OGe: Ocimum gratissimum ethyl-acetate fraction; OGb: Ocimum gratissimum n-butanol fraction; OGa: Ocimum gratissimum aqueous fraction. Negative sign (−) before a figure signifies increase in fasting blood glucose.