Skip to main content
. 2017 Oct 11;4(4):73. doi: 10.3390/medicines4040073

Table 4.

Percentage decrease in fasting blood glucose of diabetic rats, after treatment with Ocimum gratissimum leaf fractions (250 mg/kg bw).

Groups FBS (mg/dL) Day 0 Percentage Decrease after Treatment (%)
Day 7 Day 14 Day 21 Day 28
NC 83.7 ± 5.9 a 2.4 ± 6.1 b,1 1.6 ± 7.0 b,1 −0.9 ± 5.6 b,1 0.6 ± 5.6 b,1
DC 303.3 ± 15.7 b −22.3 ± 7.0 a,3 −40.6 ± 8.0 a,1,2 −44.6 ± 13.0 a,1,2 −50.5 ± 11.5 a,1
OGh 347.9 ± 7.9 c,d 10.8 ± 4.4 b,c,1 17.8 ± 3.9 c, 1,2 20.3 ± 3.8 c,2 30.6 ± 5.0 c,3
OGc 365.4 ± 14.6 d 21.8 ± 3.0 d,1 30.6 ± 7.5 d,e,1,2 40.6 ± 6.4 d,2 54.7 ± 6.6 e,3
OGe 313.2 ± 21.1 b 12.8 ± 9.4 c,1 20.4 ± 9.9 c,d,1,2 25.6 ± 8.9 c,1,2 32.6 ±5.10 c,2
OGb 389.2 ± 10.2 e 13.6 ± 5.3 c,d,1 37.9 ± 7.9 e,2 49.7 ± 7.3 d,2 63.5 ± 4.8 f,3
OGa 339.0 ± 8.0 c 17.9 ± 4.0 c,d,1 19.9 ± 4.0 c,1 29.0 ± 3.6 c,2 44.4 ± 10.9 d,3
PC 421.2 ± 38.2 f 10.1 ± 11.5 b,c,1 26.7 ± 14.1 d,1,2 49.1 ± 7. 8 e,2 71.7 ± 2.2 f,3

Data are presented as mean ± SD of 6 animals per group. Values with different superscript down the column and different alphabet across the column indicate significant difference (p < 0.05). NC: Normal control; DC: Diabetic control; PC: Positive control (Metformin 500 mg/kg bw); OGh: Ocimum gratissimum n-hexane fraction; OGc: Ocimum gratissimum chloroform fraction; OGe: Ocimum gratissimum ethyl-acetate fraction; OGb: Ocimum gratissimum n-butanol fraction; OGa: Ocimum gratissimum aqueous fraction. Negative sign (−) before a figure signifies increase in fasting blood glucose.