Table 7.
Effects of treatment with Ocimum gratissimum leaf fractions (250 mg/kg bw) for 28 days on serum lipid profile of diabetic rats.
| Groups | TC (mg/dL) | HDLC (mg/dL) | TG (mg/dL) | LDLC (mg/dL) | TC/HDL (mg/dL) |
|---|---|---|---|---|---|
| NC | 78.0 ± 7.6 a | 58.6 ± 5.8 e | 73.6 ± 8.0 a | 4.7 ± 9.2 a | 1.3 ± 0.2 a |
| DC | 176.7 ± 11.8 d | 17.8 ± 2.6 a | 448.7 ± 11.4 e | 69.1 ± 10.3 c,d | 10.1 ± 1.3 f |
| OGh | 109.5 ± 10.3 b | 35.1 ± 3.3 c | 119.2 ± 7.4 d | 50.6 ± 13.2 b,c | 3.2 ± 0.5 b,c |
| OGc | 117.1 ± 10.7 b | 32.3 ± 4.7 b,c | 99.2 ± 5.6 c | 65.0 ± 9.7 c | 3.7 ±0.5 c,d |
| OGe | 111.2 ± 7.7 b | 27.5 ± 4.9 b | 115.1 ± 5.7 d | 60.7 ± 8.9 b,c | 4.1 ± 0.7 d,e |
| OGb | 102.6 ± 24.6 b | 41.4 ± 6.6 d | 87.0 ± 6.8 b | 43.8 ± 24.3 b,c | 2.5 ± 0.6 b |
| OGa | 117.4 ± 18.9 b | 28.2 ± 5.3 b | 101.8 ± 6.8 c | 68.8 ±18.1 c,d | 4.3 ± 0.8 d,e |
| PC | 137.5 ± 12.8 c | 29.6±5.9 b,c | 105.2 ± 6.3 c | 86.9 ± 17.7 d | 4.8 ± 1.2 e |
Data are presented as mean ± SD of 6 animals per group. Values with different superscript down the column indicate significant difference (p < 0.05). TC: Serum Total cholesterol; HDLC: Serum High density lipoprotein cholesterol; LDLC: Serum Low density lipoprotein cholesterol; TG: Serum Triglyceride; NC: Normal control; DC: Diabetic control; PC: Positive control (Metformin 500 mg/kg bw); OGh: Ocimum gratissimum n-hexane fraction; OGc: Ocimum gratissimum chloroform fraction; OGe: Ocimum gratissimum ethyl-acetate fraction; OGb: Ocimum gratissimum n-butanol fraction; OGa: Ocimum gratissimum aqueous fraction.