Figure 4.
Pemetrexed synthetic pathway: 2,6-diamino-4(3H)-pyrimidinone as starting material to obtain substituted pyrrolo [2,3-d] pyrimidine, which reacts in a conventional peptide coupling with glutamate.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.