Fig. 1. Conserved motifs of odorant receptors (ORs).

(A) Sequence alignment of three representative ORs from Human, rat, and mouse [NP_003544.2, NP_667218.1, NP_001006610.1] that have most identical sequences with conserved motif. Conserved motifs were indicated as red color, and the transmembrane domains were boxed in yellow color and numbered. 18 amino acid conserved residues were underlined in green color. (B) Cartoon of an OR sitting in the cellular plasma membrane. Seven transmembrane domains are numbered. The location of the conserved motif at the TM7-C terminal was represented in green colored line and its amino acid sequences are indicated.