Abstract
The availability of in office Cone Beam CT (CBCT) scanners, dental implant planning software, CAD CAM milling, and rapid printing technologies allow for the precise placement of dental implants and immediate prosthetic temporization. These technologies allow for flapless implant placement, or open flap bone reduction for “All on 4” techniques with improved preoperative planning and intraoperative performance. CBCT permits practitioners in an office setting with powerful diagnostic capabilities for the evaluation of bone quality and quantity, as well as dental and osseous pathology essential for better informed dental implant treatment. CBCT provides the convenience of in office imaging and decreased radiation exposure. Rapid printing technologies provide decreased time and high accuracy for bone model and surgical guide fabrication.
Keywords: Cone Beam CT, surgical guide, drill, planning, dental implant
Introduction
The virtual planning for the precise placement of dental implants using CT scanning, rapid printing and prototyping, optical scanning, and CAD CAM milling can now be utilized in a unified manner (1, 2). As a result of this progress from the digital technology, surgeons have improved diagnosis, with more accurate implant placement, and superior long term results. CT guided dental implant surgery allows decreased operating time, flapless procedures (3, 4), and decreased postoperative pain and swelling, and immediate temporization (5). The development of CT scanning from fan beam to spiral methods (6) has resulted in the development of in office Cone Beam CT (CBCT) scanners with decreased radiation dosage (7, 8) (Figure 1a, Figure 1b and Figure 1c) which are now widely available as standup, lie down, sitting and mobile CBCT units. Plain tomography which was developed in the 1930’s by Vallabona (9), and allowed the sectioning of an anatomic structure from the surrounding organs as a plain radiographic series of images, is the basis for CBCT. The orthopantamograph provides panoramic images and is an example of the continued use of plain tomography (10). The advent of computers, allowed the further development of plain tomography into a more sophisticated 3D imaging method. The concept for CT scanning was independently developed by Hounsfield and Cormack (11, 12), for which they were awarded the Nobel Prize in 1979 (13). Hounsfield who created the first CT scanner that imaged the brain and later the whole body using the fan beam technique at EMI was funded by records sales from “The Beatles” (14, 15). With advances in computer and scintillator technology, spiral (helical) CT scanning machines were built. Based on the work of Kalender (16, 17). it was from the helical scanners that CBCT is derived. Radon’s Transform developed in 1917 (18) (Figure 2), is the basic mathematical method for CT scanning and is based on back projection geometry (19, 20) (Figure 3).
Figure 1.
a. Fan Beam CT Scanner patient orientation, b. Cone Beam CT scanner patient orientation, and c. Cone Beam CT Flat Plane Scanner for sitting or standup.
Figure 2.
Radon’s Transform mathematical formula.
Figure 3.
Radon’s Transform back projection geometric diagram.
Methods for calculating the algorithm utilize either the Iterative Reconstruction (IR) (21), or Filtered Back Projection (FBP) (22). CBCT includes axial, sagittal, and coronal projections, 2D panoramic and lateral cephalometric images as well as 3D and oblique sagittal reformatted images (23). With 72 million studies reported in the US, CT contributes to the increased radiation exposure to patients (24). Patients can be scanned at a significant reduction in radiation exposure using CBCT with powerful algorithms and lowered cancer risk compared to Helical CT (25, 26). In developed countries increased exposure of populations to radiation from CT scans has lead to considerable concern for increased cancer rates (27, 28). Clinicians understanding of the radiation exposure of patients from plain and CT radiography is important to help decide when such studies are appropriate and to be able to answer patient concerns. Therefore, it is of importance to understand the radiation dosage from plain dental radiography and CBCT. The radiation exposure from plain dental radiography has been reviewed by Ludlow et al. (29) with the effective doses as: Full Mouth Exposures=34.9-170.7, (μSv), Bitewing=5(μSv), and Panoramic =14.2-24.3(μSv) and can be compared to the background annual radiation exposure from the environment = 3,100(μSv) (30) . CBCT radiation dosage has been reported by Roberts et al. (31) and is found to be: Full FOV (Field of View) 206.2 (μSv), 13 cm FOV 133.9 (μSv), 6 cm FOV high resolution maxilla 93.3(μSv), 5 cm FOV high resolution mandible 188.5 (μSv), 6 cm standard mandible 96.2 (μSv), and 6 cm standard maxilla 58.9 (μSv). Different CBCT machines FOV radiation can vary from 51.7 to 193.4 (μSv). The average radiation dosage from CBCT is substantially lower at 5-10% (51.7 to 193.4 (μSv) when compared to a medical helical CT scan of the head = 2000 (μSv) (32) . Concern regarding the lack of uniformity of various CBCT scanners actual radiation doses has been reported (33). Depending on the CBCT scanner and the FOV the radiation dosage equivalent to a multiple of panoramic radiographs which ranges from 2-4 (15-78 μSv) for a 12” FOV scan and1-1 ½ (5- 33μSv) for a 9” FOV scan. By comparison the greatly increased risk of cancer from radiation exposure from a full body scan has been compared to the rate of cancer in atomic bomb survivors (34). CBCT has become essential to contemporary dental implant treatment which allows the correct diagnosis through highly detailed representations of critical anatomic structures, precise measurements, and treatment planning in both 2D and 3D. CBCT images have excellent bone window resolution, but are lacking the soft tissue details of helical CT scans. Through the use of Hounsfield Units (35), range from 0-1000, in which bone =400+, water= 0, and air=1000 (36). CBCT can also provide the determination as to whether the patient has suitable bone density or not. CBCT provides imaging information regarding key anatomic structures such as the nasopalatine foramen (37) (Figure 4a and Figure 4b), mental foramina (38) (Figure 5), mandibular canals (39) (Figure 6), and sinus cavity (40) (Figure 7) positions.
Figure 4.
CBCT a. Incisive foramen axial view and b. Incisive foramen sagittal view.
Figure 5.
Mental foramen CBCT reformatted oblique sagittal view.
Figure 6.
(a)Panoramic CBCT view of right mandibular missing second molar and marking of the left mandibular canal. (b) Reformatted oblique sagittal CBCT views of right mandibular missing second molar and marking of the left mandibular canal.
Figure 7.
Reformatted oblique sagittal CBCT view of the maxillary sinus.
Visualization of these anatomic structures can help to prevent complications such as nerve injuries and injudicious sinus perforation. CBCT can also diagnose the presence of other dental or osseous pathology, whether cysts (41), impacted teeth (42), endodontic infections (43), periodontal disease (44), dental caries (44, 45), malignant (46) or benign tumors (47, 48, 49). For planning the placement of dental implants panoramic and reformatted oblique sagittal views are the most important (Figure 6a and Figure 6b) (23, 50, 51). A rapid survey of the patient’s panoramic view allows a general understanding of the dental condition, bone height, and the presence of pathology. Panoramic views require CBCT machines with Full Field of View (FOV), while machines with more limited views do not. Detailed cross sectional evaluation of the maxilla or mandible is provided by the reformatted oblique sagittal views provide information concerning the width and height of the bone (23, 50, 51). Oblique sagittal views also allow better evaluation of the posterior mandible with the ability to mark the mandibular nerve, mental foramen, and incisive nerve branches (52, 53, 54, 55) (Figure 6a and Figure 6b). For dental implant planning the oblique sagittal images (Figure 6a and Figure 6b) are the most important as they provide both the height and width dimensions as cross sectional images of the mandible or maxilla that are critical to planning dental implant trajectory and depth, and whether site development with localized bone graft augmentation is necessary. CBCT can also be utilized in extraction cases planning for simultaneous implant placement whether preoperative or following removal of the tooth (56) requires the use of the reformatted oblique sagittal views. Planning in a virtual environment allows these images to be matched to a 3D image of the bone and dental prosthesis which permits a prosthetically driven dental implant placement (57) It is then not just a matter of placing the dental implant where there is sufficient bone, but also by taking into consideration the ideal position for the fabrication of the individual crown or multiple unit prosthesis. Prosthetically driven virtual planning dental implant positions to determine screw versus cement retained restorations which will have different trajectory positions for the prosthesis and dentition. CT guided depth control ensures the precise placement of dental implants for immediate restoration such as in full arch edentulous prosthesis such as “All on 4” types of cases (58), and the avoidance of injury to the mandibular nerves, mental foramen, and maxillary sinuses. Jenson et al. (59, 60) have reported on bone reduction using the “shelf technique” for the simultaneous placement of dental implants and prosthesis.
Modular templates with an outer framework containing a guide way can be utilized for bone reduction with a separate modular part containing master drill sleeves inserted for implant drill sequence and implant placement (61, 62). CBCT data can also be uploaded to other software applications and create a STL output for the fabrication of custom patient specific surgical drill guides by rapid printing or prototyping (Figure 8).Through preoperative planning (63), the CT based patient specific surgical drill guide allows the surgeon to achieve the optimal implant positions. The use of presurgical software planning permits the determination of the need for site development with bone grafting, or if adequate bone height and width is present. Whether simple or complex alveolar ridge augmentation, sinus bone augmentation via indirect and direct techniques, sites for immediate extraction and implant placement, teeth with decay, periodontal or endodontic infections can be preoperatively determined by CBCT and diagnosed. A variety of methods for the acquisition of the data which can include single scan, dual scan, combined CT and optical methods. Optical methods can include desktop scanning of a dental model, and the intraoral scanning of the patient’s dentition (64). The data sets can be merged so as to create a clean data set to manage the artifacts created from the scatter caused by gamma radiation particles striking metallic dental restorations (65) (Figure 9).
Figure 8.
Rapid printed patient specific CT guided surgical drill template and example with scaffolding from 3D printer still attached.
Figure 9.
3D CBCT view of dental artifacts.
In order to perform the dual scan procedure, it is necessary to have a laboratory fabricated radiographic template which contains at least 6 gutta percha or metal bead fiducial markers (Figure 10). These fiducial markers permit the merger of two data sets (23). One data set is of the patient with the radiographic template correctly seated in the mouth. The second data set is achieved by imaging of the radiographic template by itself in a styrofoam box (Figure 11). The purpose of using these two data sets is to produce an artifact free image of the radiographic template which has a clean image of the occlusal surfaces can then be manipulated by the planning software to contain the desired implant trajectories and a surgical drill guide is then rapid printed from the STL file.
Figure 10.
Laboratory fabricated radiographic template with 6 gutta percha markers.
Figure 11.
Radiographic template is contained within Styrofoam box for second scan in a CBCT Flat Plane Scanner. Styrofoam does not appear in the CBCT image because of its low density.
Artifacts created from the gamma radiation striking the patient’s dental metallic restorations create scatter effects in the 2D and 3D image that obscures the dental anatomy. The artifact obscured image prevents the production, of a well fitting surgicaldrill guide. The patients existing partial or complete all acrylic dentures can be used for the dual scanning process by placing the fiducial markers into the actual prosthesis which converts the removable partial or complete denture into a radiographic template. The two data sets whether from the existing dentures or a laboratory fabricated radiographic template are then uploaded to a fileshare at a vendor’s website so that the data sets can be merged, converted and then returned to the dentist for use in the planning software. The dual scan technique allows a clean image of the patient’s dentition free of artifacts allows prosthetic planning and rapid printing of an accurately fitting drill guide for tooth borne cases, and is highly accurate because of the fiducial marker registration. Software planning allows for the conversion of the virtual image of the patient’s bony anatomy and planned dental implant positions and depths and by digital subtraction of the virtual template the fabrication of a surgical drill template produced by rapid manufacturing and rapid printing technologies (66) (Figure 12).
Figure 12.
Rapid printed surgical template with metal master drill sleeves.
Once converted from the virtual image by rapid printing, the actual surgical drill guide will contain the precise information regarding the planned implant trajectories and surgical depth to be transferred to the patient. These guides can be bone borne, tooth borne, mucosal borne or in a combination of seatings (67). Stabilization of surgical guides on the jaw can be performed by the surgeon’s nondominant hand or assistant pressing the guide down, or fixation with surgical pins or screws. These screw or pin stabilizers channels can be planned in the software and produced as channels in the surgical drill guide (67). The drill guides once fabricated have metal sleeves placed into the trajectories so that drill bits can be placed directly in them or through handles sized for different diameter drill bits fit into the master sleeves. Many dental implant manufacturers provide their own CT guided implant surgery drill kits. These surgical kits provide all of the instrumentation necessary to perform CT guided implant surgery using rapid printed drill guides. When the procedure begins, if a flapless technique is being performed, after stabilizing the surgical drill guide, (Figure 13) the first step is to use the mucosal punch in a rotary instrument to remove a core of gingiva.
Figure 13.
Rapid printed tooth borne surgical drill guide fitted demonstrating precise fit to occlusal surfaces.
Case Report
Clinical examples of case are presented so as to elaborate the technique of CT guided dental implant placement. A 22-year-old female presented with missing anterior mandibular teeth #23-26 for dental implant placement. CBCT scan revealed an anterior mandibular superior alveolar buccal ridge inadequate width thickness. A radiographic guide was fabricated and dual scan imaging protocol performed and virtual planning for dental implants teeth #23 and 26 with virtual conversion of the radiographic template into a surgical drill guide STL file which was rapid printed. The metal drill sleeves were inserted and surgery was performed with removal of the bone graft fixation screws and placement of dental implants teeth #23 and 26. After 4 months the implants were uncovered and fixed implant retained prosthesis was fabricated and placed. (Dental implant surgery: Dr. Alex M. Greenberg, NY, NY, Prosthodontics: Dr. Joel Hirsch, NY, NY). (Figure 14, Figure 15, Figure 16, Figure 17, Figure 18, Figure 19 ).
Figure 14.
Anterior mandible missing teeth #23-26 with inadequate superior alveolar ridge width thickness. Postoperative CBCT reformatted oblique sagittal view mandible missing teeth #23-26 after bilateral chin block corticocancellous grafts repositioned to the buccal superior alveolar ridge with screw fixation region teeth #23-26.
Figure 15.
CBCT 3D view of radiographic guide.
Figure 16.
Virtual planning environment in all planes with 3D view of radiographic template superimposed on transparent bone image with dental implant trajectories teeth #23 and 26 (ImplantMaster iDent Imaging, Inc, New York, NY).
Figure 17.
a and b. Virtual planning environment oblique sagittal view of dental implant teeth #23 (a) and 26 (b) (ImplantMaster iDent Imaging, Inc, New York, NY).
Figure 18.
Rapid printed surgical drill guide. (iDent Imaging, Inc, New York, NY, Figure used with Permission, Greenberg AM Ed. Digital Technologies in Craniomaxillofacial Surgery, Springer Verlag New York, In Press).
Figure 19.
Postoperative completion film of implant retained fixed prosthesis teeth #23 and 26.
Conclusion
CBCT has become an important in office or scanning center based dental imaging technology, providing powerful diagnostic capabilities and practical applications. Software planning for dental implant placement allows preoperative diagnosis, precise planning and trajectories, and the fabrication of rapid printed surgical drill guides. New technologies of CAD CAM milling, optical scanning, and modular implant fabrication will allow further advances in this rapidly developing aspect of dental implant treatment.
Footnotes
Source of funding: None declared.
Conflict of interest: Author disclosed receiving a grant from Straumann Group as a relevant financial activity outside the submitted work. Author disclosed holding the rights of intellectual properties (issued patent, number: US 9,050,665 and US 8,750, 590) for two items mentioned in this article.
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