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. 2017 Nov 28;4(4):ofx262. doi: 10.1093/ofid/ofx262

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© The Author(s) 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Hazard ratios (HRs) with 95% confidence intervals (CIs) for the risk of clinical events associated with 2× higher baseline biomarker levels in START (n = 4299). HRs were estimated in separate proportional hazards models, pooled across treatment groups, adjusted for age, gender, and treatment group, and stratified by geographic location. HRs are per 2× higher biomarker(s). Biomarker associations with event risk were homogeneous across treatment groups, except for sVCAM with AIDS (higher HR in the deferred group) and sICAM with SNA (higher HR in the immediate group). Abbreviations: IL = interleukin; hsCRP = high-sensitivity C-reactive protein; SAA = serum amyloid A; sICAM = soluble intercellular adhesion molecule; sVCAM = soluble vascular cellular adhesion molecule.