Figure 4.

Biomarker changes from baseline to month 8 with immediate vs deferred art initiation in START (n = 3980). The percentage change (95% CI) from baseline to month 8 for each of the 7 biomarkers, adjusted for baseline level, is plotted for both the immediate (red circles) and deferred (blue squares) ART groups. The absolute difference between immediate and deferred groups for the percentage change from baseline to month 8 is presented below the x-axis (with P-values) for each of the biomarkers. Abbreviations: CI = confidence interval; hsCRP = high-sensitivity C-reactive protein; IL = interleukin; sICAM = soluble intercellular adhesion molecule, sVCAM = soluble vascular cellular adhesion molecule.