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. 2017 Nov 26;18(12):2530. doi: 10.3390/ijms18122530

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) The miR-210 binding site of BCL11A is conserved through evolution. The sequences of human (Homo sapiens, NM_022893.3, nucleotides 789–798), Sumatran orangutan (Pongo abelii, XM_002812009.2, nucleotides 709–718), bovine (Bos taurus, NM_001076121.1, nucleotides 787–796), mouse (Mus musculus, NM_016707.3, nucleotides 896–905), rat (Rattus norvegicus, NM_001191683.1, nucleotides 803–812), red junglefowl (Gallus gallus, NM_001031031.1, nucleotides 812–821), frog (Xenopus tropicalis, NM_001079189.1, nucleotides 592–601) are indicated. Nucleotide variations with respect to H. sapiens BCL11A sequences are boxed; (B) Location of the miR-210 binding site within the BCL11A isoforms.