Table 1.

Glioblastoma aptamers and their SELEX methods.

Aptamer	Target	SELEX Method	Positive Selection	Negative Selection	Reference(s)
A3, A4	Unknown	Differential cell-SELEX	CD133+ TIC	CD133− cells; human neural progenitor cells	[72]
TTA1	Tenascin-C	Crossover-SELEX	U251 cells; human Tenascin-C	No negative selection	[66,73]
GBI-10	Tenascin-C	Cell-SELEX	U251 cells	No negative selection	[74,75]
Gint4.T	PDGFRβ	Cell-SELEX	U87MG cells	No negative selection	[76,77]
GL21.T	Axl	Differential cell-SELEX	U87MG cells	T98G cells	[77,78,79,80]
U2	EGFRvIII	Differential cell-SELEX	U87MG-EGFRvIII cells	U87MG cells	[81]
Aptamer 32	EGFRvIII	Differential cell-SELEX	U87MG-EGFRvIII cells	U87MG cells	[82,83,84]
E07	EGFR; EGFRvIII	Protein-SELEX	Human EGFR	No negative selection	[85,86,87]
GMT 3–9	Unknown	Differential cell-SELEX	A172 cells	No negative selection	[88]
GBM128, GBM131	Unknown	Differential cell-SELEX	U118-MG cells	SVGp12 cells	[89]