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. 2017 Dec 1;18(12):2593. doi: 10.3390/ijms18122593

Table 1.

The expression of aquaporin (AQP) isotypes (P: protein or R: mRNA) in different mammalian species (h: human; r: rat; m: mouse; c: cattle; o: ovine; p: pig) during pregnancy. aec: apoptotic epithelial cells; acl: apical cell layers of cervical epithelium; bcl: basal cell layers of cervical epithelium; bz: basal zone; cp: complete placenta; ec: epithelial cells; em: endometrium; fc: fibroblast cells; gc: granulose cells; icm: inner-cell mass of blastocytes; lz: labyrinth zone, mm: myometrium; mt: mural trophectoderm of blastocyst; pv: placenta villi; st: syncytiotrophoblast cells; tec: trophoblast epithelial cells; vec: vascular epithelial cells.

Sites of Expression AQP1 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP8 AQP9 AQP11 AQP12
Oocytes/blastocytes (implantation) h-gc-R h-gc-R h-gc-R h-gc-R h-gc-R h-gc-R h-gc-R m-icm-P h-gc-R
m-mt-P
h-gc-R h-gc-R
Uterus (implantation) r-mm-P
m-mm-P+R
p-P
h-em-P+R h-em-P+R m-mm-P+R
c-em-R
m-mm-P+R
r-mm-P
p-P
- - m-mm-P r-P+R
p-P
- -
Amnionic membrane h-P+R
o-P+R
m-fc-P
- h-P+R
o-P+R
m-ec, fc-P
- - - - h-P+R
o-P+R
m-ec-P
h-P+R
o-P+R
m-aec-P
h-P+R
o-P+R
-
Placenta h-pv-R
r-bz, lz-P
m-vec-P+R
o-vec-P+R
- h-pv-R
r-R
m-tec-P+R
o-tec-P+R
h-pv-R
h-st, ec-P
h-pv-R - - h-pv-R
r-bz, lz-P
m-P+R
o-tec-R
h-pv-R
r-cp, bz, lz-P
m-R
h-pv-R -
Uterus (late pregnant) r-P+R r-P+R r-P+R r-P+R - - r-P+R r-P+R - -
Cervix (late pregnant) - - m-bcl-P+R m-acl
P+R
m-acl
P+R
- - m-acl
P+R
- - -