Table 7.

Change in total amounts of EGFR and pEGFR in whole cell lipids and lipid rafts with EPA:DHA mixtures in human BC cell lines.

Citation	Cell Line	Concentration of EPA or DHA (µM)	Exposure (Hours)	Change in EGFR *
Schley, Brindley and Field [13]	MDA-MB-231	60 EPA + 40 DHA	72	NS Δ in whole cell EGFR ** ↑50% whole cell pEGFR ↓lipid raft EGFR **
		45 EPA + 30 DHA + 75 LA		NS Δ in whole cell EGFR ** ↑21% whole cell pEGFR ↓lipid raft EGFR **

EPA = eicosapentaenoic acid; DHA = docosahexaenoic acid; LA = linoleic acid; EGFR = epidermal growth factor receptor; pEGFR = phosphorylated EGFR; NS Δ = no significant change; “↑” denotes significant increase (p < 0.05); “↓” denotes significant decrease (p < 0.05); “%” = percent change from control condition; * Relative to control conditions; ** Researchers did not quantify percent change in bands from control condition in Western Blot Analysis.