Table 1.
Patients’ demographics in each cohort.
| Non-UC a | UC b | p Value a vs. b | ||||
|---|---|---|---|---|---|---|
| HV | n, (%) | PC | n, (%) | n, (%) | ||
| Total patients (n) | 339 | 96 | 237 | |||
| Sex (Male, %) | 122 (36.0) | 96 (100) | 191 (80.6) | <0.001 | ||
| Median age (IQR 1) | 68.0 (63–73) | 74.0 (68–78) | 70.0 (62–75) | 0.700 | ||
| Former or current smoker | 75 (22.1) | 18 (18.8) | 71 (29.9) | 0.101 | ||
| Stone former | 4 (1.2) | 0 (0) | 0 (0) | 0.184 | ||
| BPH 2 | 7 (2.1) | 0 (0) | 0 (0) | 0.145 | ||
| HSPC 3 | 0 (0) | 96 (100) | 0 (0) | <0.001 | ||
| hematuria+ | 0 (0) | 0 (0) | 186 (78.5) | <0.001 | ||
| Urine Cytology Class | ||||||
| I, II | 81 (34.2) | |||||
| III | 58 (24.5) | |||||
| IV | 16 (6.7) | |||||
| V | 82 (34.6) | |||||
| Tumor Location of UC | ||||||
| Bladder | 177 (67.6) | |||||
| Renal pelvis | 27 (11.4) | |||||
| Ureter | 28 (11.8) | |||||
| Multiple | 4 (1.7) | |||||
| Tumor Grade of UC | ||||||
| Low grade noninvasive | 68 (28.7) | |||||
| High grade noninvasive | 43 (18.1) | |||||
| Muscle invasive | 109 (45.9) | |||||
| Lymph node stage N1 | 0 (0.0) | 20 (8.4) | 0.115 | |||
| Metastatic disease | 4 (4.2) | 47 (19.8) | 0.010 | |||
1 IQR, Interquartile range; 2 BPH, benign prostatic hyperplasia; 3 HSPC, hormone sensitive prostate cancer; HV: healthy volunteers; PC: prostate cancer. a non-urothelial carcinoma, non-UC; b urothelial carcinoma, UC.