| AE | adverse event |
| AUC0–24 | area under the plasma drug concentration-time curve from 0 to 24 h |
| AUC0–∞ | area under the plasma drug concentration-time curve from 0 to infinity |
| AUC | area under the plasma drug concentration-time curve |
| AUEC | area under the effect-time curve |
| CI | confidence interval |
| CL/F | apparent oral clearance |
| Cmax | maximum plasma concentration |
| Emax | maximum effect |
| ECG | electrocardiogram |
| EDTA | ethylene di-amine tetra acetic acid |
| FEV1 | forced expiratory volume in 1 s |
| FVC | forced vital capacity |
| HR | heart rate |
| LS | least squares |
| o.d. | once daily |
| PD | pharmacodynamics |
| PK | pharmacokinetics |
| S1P | sphingosine-1-phosphate |
| S1P1R | S1P1 receptor |
| SD | standard deviation |
| t1/2 | terminal half-life |
| tmax | time to reach maximum concentration |
| Vss/F | apparent volume of distribution at steady-state |
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