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Scheme for Zinc (Zn) storage and distribution in the body. Dietary Zn is absorbed in the small intestine and distributed to the peripheral tissues, including skeletal muscle (60%), bone (30%), skin (5%), and other tissues (5%). Zn deficiency causes various abnormalities in humans and animal models, such as growth retardation, immune dysfunctions, diarrhea, and skin diseases, including acrodermatitis enteropathica (AE).
