Table 5.
Significant risk gene modules.
| Cluster | Score | Nodes | Edges | Node IDs |
|---|---|---|---|---|
| 1 | 20 | 20 | 190 |
ASB15, HECW2, UBE2D1, NEDD4L, ANAPC5, PJA2 TRIM39, UBE2R2, UBE2D4, CDC27, TRIM9, ZBTB16 LONRF1, PARK2, FBXL13 *, FBXO22, RNF19B, LMO7 RNF217, FBXO32 |
| 2 | 6.1 | 21 | 61 |
SYNJ1, KIT, PIK3C2G, PTPN11, PIK3C2B, SYNJ2 RUNX1, ITSN2, PLCB1, CDH2, DNM3, SYT1, CTTN WDFY2 *, CHRM2, CCND2, MITF, PLCG2, CDK6, ETV6, SH3GL2 |
| 3 | 5.5 | 13 | 33 | MLL, bFGF(FGF2) *, BUB1B, BARD1, RB1, DICER1, RAD50, RAD51, BCL2, CDH5, SMARCA2, ABL1, CCND3 |
| 4 | 4.182 | 12 | 23 |
AKT3, PTEN, ITPR1, PRKCE, GNB5, CDK1 ERBB4, GNG7, RAF1, GSK3B, PPM1B, MAP3K1 |
| 5 | 3 | 3 | 3 | FARS2, RAD51B, MTHFD1L * |
* core hub genes.