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Effect of vitamin D and analogues on γ-secretase. (A) Analysis of γ-secretase activity in living SH-SY5Y wt cells (n ≥ 5). (B) mRNA level of the γ-secretase component nicastrin determined by RT-PCR analysis (n = 3). Error bars represent the standard error of the mean. Asteriks show the statistical significance calculated by unpaired Student’s t test (* p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001).
