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. 2017 Dec 20;18(12):2777. doi: 10.3390/ijms18122777

Figure 2.

Figure 2

Effect of IL-18Rα on the survival and blood urea nitrogen (BUN) level in the development of AKI after LPS injection. (A) Survival of WT and IL-18Rα KO mice subjected to sepsis by LPS injection. Mice were evaluated 2×/day until 120 h post-LPS injection (WT n = 13; IL-18Rα KO mice n = 18; **** p < 0.001). (B) Renal function of WT and IL-18Rα KO mice at 0, 18 and 120 h before and after LPS injection, assessed by BUN levels. The data are the mean values ± SEM (** p < 0.01, WT vs. IL-18Rα KO mice).