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. 2018 Jan 3;18:2. doi: 10.1186/s12935-017-0500-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Silencing of IRE1α blocked the conversion of LC3-I to LC3-II in miR-200c-3p-transfected PC-3 cells. PC-3 cells were transfected with control, IRE1α, or PERK short interfering RNAs (siRNAs). The following day, control or miR-200c-3p mimics were transfected into siRNA-treated cells. One day after the second transfection, western blotting was performed to determine the levels of IRE1α, PERK, LC3-II, and β-actin