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. 2017 Nov 23;17(12):2701. doi: 10.3390/s17122701

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Single-shot measurement setup (a) Front view: consists of: a heater module, a selective deposited molecularly imprinted polymer (MIP) layer on an aluminum substrate, a PDMS flow cell and 3 temperature sensors which is here shown as a cross section of the finished flow cell. (b) The flow cell occupies a total area of 30 × 30 mm² and contains one centralized inlet (1), two parallel sensing areas of 9 mm² each (2) with integrated thermocouples (3) and a pumping area (4). The volumetric flow rate of the sample fluid can be controlled by changing the width of the channel in position (5). (c) The height of the flow cell is 0.6 mm, and the vertical pump is 8 mm high. Whole blood samples can be added to the inlet. The measurements can be carried out as single-shot, without a stabilization step in buffer solution.

Single-shot measurement setup (a) Front view: consists of: a heater module, a selective deposited molecularly imprinted polymer (MIP) layer on an aluminum substrate, a PDMS flow cell and 3 temperature sensors which is here shown as a cross section of the finished flow cell. (b) The flow cell occupies a total area of 30 × 30 mm² and contains one centralized inlet (1), two parallel sensing areas of 9 mm² each (2) with integrated thermocouples (3) and a pumping area (4). The volumetric flow rate of the sample fluid can be controlled by changing the width of the channel in position (5). (c) The height of the flow cell is 0.6 mm, and the vertical pump is 8 mm high. Whole blood samples can be added to the inlet. The measurements can be carried out as single-shot, without a stabilization step in buffer solution.