Table 2.

The betweenness degrees of proteins in the identified subnetwork

Protein	Betweenness	Protein	Betweenness	Protein	Betweenness
AKT1	112	PDGFR β	14	LEF1	8
PIK3R1	112	IGF1R	14	TCF7L1	8
p53	64	ERBB2	14	BAD	8
MDM2	64	INSRR	14	Caspase9	8
EP300	56	FGFR1	14	TCF7	8
HER1	56	FGFR2	14	mTOR	8
Grb2	42	I κ B α	8	AR	8
β -catenin	40	NF- κB	8	FOXO1	8
RELA	16	p27	8	TCF7L2	8
PDGFR α	14	p21	8

The bold font is used to highlight the identified important proteins of PI3K/Akt and MAPK signaling pathways