Fig 2.

IGS in patients with early RA predicts worse disease activity, a poorer response to initial therapy, and increased glucocorticoid requirements. Patients with early RA (n = 32) had baseline IGS calculated and disease activity parameters assessed at 6 months after diagnosis and initiation of treatment. A, Plot depicts age- and sex-corrected multiple regression between baseline IGS and DAS28 scores at 6 months. B, Relationship between the probability of achieving a good EULAR response at 6 months and baseline IGS (nominal logistic regression, age and sex corrected). C, The plot depicts the relationship between the probability of receiving additional glucocorticoids in the first 6 months after diagnosis and baseline IGS. Numbers denote the number of additional glucocorticoid administrations (0-3) in the first 6 months. Baseline IGS significantly predicted additional glucocorticoid requirements (ordinal logistic regression with bootstrap probabilities included, P = .0003). The higher the baseline IGS, the greater the probability that patients fall into the regions indicating 1 or more additional glucocorticoid doses.