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. 2017 Dec 28;18(Suppl 14):552. doi: 10.1186/s12859-017-1893-4

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — An illustrative example showing the components directly connected to gene 1. In the Boolean function {AND, OR, NOT}={∧,∨,−}. Based on the regulating function of gene 1, it is up-regulated if gene 5 is up-regulated and genes 2 and 3 are down-regulated