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. 2017 Dec 28;18(Suppl 14):552. doi: 10.1186/s12859-017-1893-4

Table 3.

The set of constraints extracted from the regulating functions and pathways for the TP53 network. Constraints extracted from the Boolean regulating functions in Table 2 corresponding to the pathway in Fig. 3(b) used in MKDIP-E, MKDIP-D, MKDIP-R (left). Constraints extracted based on [36] from the pathway in Fig. 3(b) used in RMEP, RMDIP, REMLP (right)

(a) MKDIP Constraints (b) Constraints in Methods of [36]
Node Constraint Node Constraint
v 2 E p[P(v 2=0|v 4=1)]≥1−ε 1 v 2 E p[P(v 2=0|v 4=1)]≥1−ε 1
v 2 E p[P(v 2=1|v 4=0)]≥1−ε 2 v 5 E p[P(v 5=1|v 2=0,v 4=1)]≥1−ε 2
v 5 E p[P(v 5=0|v 2=1)]≥1−ε 3
v 5 E p[P(v 5=1|v 2=0,v 4=1)]≥1−ε 4