Table 3.
The set of constraints extracted from the regulating functions and pathways for the TP53 network. Constraints extracted from the Boolean regulating functions in Table 2 corresponding to the pathway in Fig. 3(b) used in MKDIP-E, MKDIP-D, MKDIP-R (left). Constraints extracted based on [36] from the pathway in Fig. 3(b) used in RMEP, RMDIP, REMLP (right)
(a) MKDIP Constraints | (b) Constraints in Methods of [36] | ||
---|---|---|---|
Node | Constraint | Node | Constraint |
v 2 | E p[P(v 2=0|v 4=1)]≥1−ε 1 | v 2 | E p[P(v 2=0|v 4=1)]≥1−ε 1 |
v 2 | E p[P(v 2=1|v 4=0)]≥1−ε 2 | v 5 | E p[P(v 5=1|v 2=0,v 4=1)]≥1−ε 2 |
v 5 | E p[P(v 5=0|v 2=1)]≥1−ε 3 | ||
v 5 | E p[P(v 5=1|v 2=0,v 4=1)]≥1−ε 4 |