Table 2.
Gene | DRG expression | Gene | Muscle expression |
---|---|---|---|
GFRα3 | 4.5 ± 24% | Artemin | − 38.1 ± 43% |
IL6R | − 20.8 ± 46% | GDNF | 42.5 ± 26% |
P2X4 | 108.3 ± 15% * | IL-1β | − 7.6 ± 62% |
P2Y1 | − 6.3 ± 22% | IL-6 | − 44.3 ± 53% |
TNFαR | − 20.7 ± 45% | MCP-1 | 53.4 ± 75% |
NGF | − 14.6 ± 15% | ||
NT-3 | − 10.5 ± 25% | ||
TNFα | − 2.5 ± 29% |
Values indicate percentage change relative to sex- and age-matched naïve controls ± error of the difference in means (n = 6–11 per condition). *P < .05 vs. naïve obtained via Mann-Whitney Rank-Sum tests for each gene on raw sample ∆Cts, followed by the false discovery rate multiple comparisons correction within each tissue type