Table 2.
Richness, alpha-diversity, and abundance by nasal swab microbiota profile
Haemophilus-dominant profile, n = 59 (7.2%) | Moraxella-dominant profile, n = 106 (13.0%) | Staphylococcus-dominant profile, n = 363 (44.5%) | Corynebacterium-dominant profile, n = 109 (13.4%) | Enterobacter-dominant profile, n = 61 (7.5%) | Mixed profile, n = 117 (14.4%) | |
---|---|---|---|---|---|---|
Richness, median (IQR) | ||||||
Number of genera | 11 (8–9) | 15 (5–23) | 4 (2–7) | 8 (5–12) | 4 (3–6) | 18 (10–27) |
Alpha-diversity, median (IQR) | ||||||
Shannon index | 0.77 (0.37–1.15) | 1.03 (0.50–1.39) | 0.11 (0.01–0.48) | 0.89 (0.53–1.15) | 0.37 (0.07–0.70) | 1.44 (1.11–1.80) |
Relative abundance of 10 most abundant genera, mean (SD) | ||||||
Staphylococcus | 0.05 (0.08) | 0.04 (0.07) | 0.78 (0.35) | 0.07 (0.13) | 0.03 (0.06) | 0.29 (0.24) |
Corynebacterium | 0.02 (0.03) | 0.05 (0.08) | 0.02 (0.05) | 0.59 (0.27) | 0.00 (0.01) | 0.07 (0.09) |
Moraxella | 0.06 (0.09) | 0.48 (0.33) | 0.01 (0.02) | 0.03 (0.06) | 0.01 (0.03) | 0.13 (0.13) |
Haemophilus | 0.74 (0.20) | 0.04 (0.09) | 0.00 (0.02) | 0.03 (0.07) | 0.01 (0.03) | 0.06 (0.12) |
Dolosigranulum | 0.02 (0.04) | 0.04 (0.07) | 0.04 (0.17) | 0.13 (0.17) | 0.01 (0.03) | 0.07 (0.14) |
Streptococcus | 0.03 (0.06) | 0.05 (0.08) | 0.04 (0.14) | 0.04 (0.11) | 0.01 (0.02) | 0.14 (0.21) |
Enterobacter | 0.01 (0.06) | 0.01 (0.04) | 0.00 (0.02) | 0.00 (0.01) | 0.52 (0.41) | 0.03 (0.09) |
Bacillus | 0.00 (0.01) | 0.00 (0.00) | 0.05 (0.20) | 0.00 (0.00) | 0.00 (0.00) | 0.01 (0.08) |
Enterococcus | 0.00 (0.02) | 0.01 (0.02) | 0.04 (0.17) | 0.01 (0.05) | 0.01 (0.05) | 0.01 (0.06) |
Acinetobacter | 0.00 (0.00) | 0.12 (0.30) | 0.00 (0.01) | 0.00 (0.00) | 0.02 (0.09) | 0.02 (0.08) |
Summary of the richness, alpha-diversity (Shannon index), and relative abundances of the most common genera for each of the nasal swab microbiota profiles as determined by partitioning around the medoid (PAM) clustering. The 10 most abundant genera were determined by taking the sum of the abundances for each genus over all the samples and are listed in order from most to least abundant