Table 1. Neutralizing antibody titers in CM before and after immunization with TV-MT.
Day | Monkey ID | Mean NT50^ | |||
---|---|---|---|---|---|
CM1-2706 | CM3-1700 | CM6-7056 | |||
DENV-1 | -6 | 51.7 | 52.2 | <20.0 | 41.3 |
30 | 286.8 | 134.2 | 85.5 | 168.8 | |
97 | 29.5 | 31.0 | <20.0 | 26.8 | |
DENV-2 | -6 | 28.7 | 23.8 | 28.1 | 26.9 |
30 | 1006.0 | 1639.0 | 427.1 | 1024.0 | |
97 | 156.0 | 618.0 | 93.8 | 289.3 | |
DENV-3 | -6 | 130.7 | 60.9 | <20.0 | 105.1 |
30 | 120.1 | 119.5 | 30.6 | 90.1 | |
97 | 58.1 | 97.7 | <20.0 | 58.6 | |
DENV-4 | -6 | <20.0 | <20.0 | <20.0 | 20.0 |
30 | 148.7 | 260.9 | <20.0 | 143.2 | |
97 | 24.1 | 24.9 | <20.0 | 23.0 |
^for mean calculation, values <20 were considered 20.