Table 3. Amino acid sequence conservation in epitopic regions.
CCHFV isolates were grouped according to phylogenetic relatedness as described previously [42,43] and the number of amino acid differences compared to SPU 103/87 were tabulated for each reactive peptide.
| I West Africa |
II DRC |
III South/ West Africa |
IV Asia/ Middle East |
V Europe/ Turkey |
VI Greece |
VII Mauritania |
Other | |
|---|---|---|---|---|---|---|---|---|
| G1280-1298 | 1 | 1 | 0–1 | 0–1 | 1–2 | 3 | 1 | 2 |
| G1352-1370 | 1 | 1 | 0 | 0–1 | 0–1 | 1 | 0 | 1 |
| N19-37 | 0 | 1 | 0 | 0–1 | 0–1 | 0 | ||
| N28-46 | 1 | 0 | 0–1 | 0–1 | 2 | 1 | ||
| N136-154 | 1 | 0 | 0 | 0–2 | 0 | 2 | ||
| N145-163 | 1 | 0 | 0 | 0–2 | 0 | 2 | ||
| N262-280 | 2 | 3 | 0–1 | 0–3 | 2 | 6 | ||
| N271-289 | 2 | 2 | 0–1 | 0–3 | 0–1 | 4 | ||
| N298-316 | 2 | 2 | 0–1 | 0–1 | 2 | 2 | ||
| N343-361 | 0 | 0 | 0–1 | 0–1 | 0 | 0 | ||
| N397-415 | 0 | 0 | 0 | 0–1 | 0 | 0 | ||
| N406-424 | 1 | 0 | 0–1 | 0 | 1 | 1 | ||
| N442-460 | 0 | 0 | 0–1 | 0–1 | 0–1 | 2 | ||
| N451-469 | 0 | 0 | 0 | 0 | 0–1 | 0 | ||
| N460-478 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| N464-482 | 0 | 0 | 0–1 | 0 | 0 | 0 |