Table 2.
Intervention effects on clinical outcomes at 11-year (median) follow-up: multivariate Cox proportional hazards regressions and Weibull accelerated failure time models (N = 240)
| Variable | All-cause mortalityb
|
Breast cancer-specific mortalityb
|
Breast cancer recurrencec
|
|||
|---|---|---|---|---|---|---|
| HR (95 % CI) | p | HR (95 % CI) | p | HR (95 % CI) | p | |
| Study condition (CBSM) | 0.21 (0.05–0.93) | .040 | 0.25 (0.05–1.11) | .068 | 0.45 (0.17–1.18) | .083 |
| Age at diagnosis | 0.91 (0.84–0.99) | .025 | 0.91 (0.83–0.99) | .025 | 0.94 (0.89–1.00) | .023 |
| Her2/neu (positive) | 2.12 (0.53–8.33) | .288 | 1.70 (0.39–7.41) | .481 | 1.85 (0.70–4.91) | .199 |
| Tumor size | ||||||
| >T2 | 3.47 (0.40–30.13) | .259 | 4.81 (0.55–42.11) | .156 | 4.65 (0.85–25.43) | .057 |
| T1c | 1.79 (0.18–17.86) | .619 | 2.34 (0.23–23.89) | .474 | 2.89 (0.54–15.38) | .195 |
| <T1c | – | .444 | – | .306 | – | – |
| Endocrine therapy (yes) | 0.25 (0.06–0.97) | .045 | 0.29 (0.07–1.28) | .102 | 0.46 (0.16–1.29) | .121 |
| Stage (invasive) | 0.45 (0.03–7.60) | .578 | –a | –a | 0.64 (0.05–7.73) | .723 |
HR hazard ratio, 95 % CI 95 % confidence interval, HER2/neu human epidermal growth receptor, CBSM cognitive-behavioral stress management
Stage of disease not included in this analysis due to large standard error
Analyzed with Cox proportional hazards models
Analyzed with Weibull accelerated failure time models