Table 3.
Intervention effects on clinical outcomes at 11-year (median) follow-up multivariate Cox proportional hazards regressions and Weibull accelerated failure time model: invasive tumor subsample only (N = 197)
Variable | Breast cancer-specific mortalitya
|
Breast cancer recurrenceb
|
||
---|---|---|---|---|
HR (95 % CI) | p | HR (95 % CI) | p | |
Study condition (CBSM) | 0.08 (0.01–0.49) | .006 | 0.24 (0.07–0.82) | .011 |
Age at diagnosis | 0.88 (0.79–0.97) | .010 | 0.94 (0.88–1.00) | .024 |
Her2/neu (positive) | 4.33 (0.81–23.21) | .087 | 2.92 (0.97–8.77) | .039 |
Tumor size | ||||
>T2 | 7.47 (0.64–87.57) | .109 | 4.61 (0.82–25.82) | .062 |
T1c | 3.61 (0.29–45.71) | .321 | 2.89 (0.67–22.18) | .111 |
<T1c | – | .266 | – | – |
Endocrine therapy (yes) | 0.28 (0.06–1.24) | .093 | 0.49 (0.17–1.43) | .174 |
Stage (III vs. I and II) | 23.46 (3.65–150.62) | .001 | 4.03 (1.05–15.46) | .026 |
HR hazard ratio, 95 % CI 95 % confidence interval, HER2/neu human epidermal growth receptor, CBSM cognitive-behavioral stress management
Analyzed with Cox proportional hazards models
Analyzed with Weibull accelerated failure time models