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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Cytoskeleton (Hoboken). 2017 Jul 24;74(9):356–366. doi: 10.1002/cm.21386

Figure 1. The presence of taxol in motility experiments does not influence the motility of multiple-kinesin cargos along GMPCPP microtubules.

Figure 1

GMPCPP microtubules were assembled in the absence of taxol. Taxol concentrations during motility experiments are indicated. (A) Histograms (i) and cumulative probability distributions (ii) of cargo run length along GMPCPP microtubules, in the presence (blue) and the absence (magenta) of taxol. Solid lines, best fits to a single exponential distribution, e−x/d. Mean run length (d ± standard error) sample size (n) are indicated. The run length distributions do not differ significantly from each other (P = 0.60, rank-sum test). (B) Histograms (i) and cumulative probability distributions (ii) of cargo velocity along GMPCPP microtubules, in the presence (blue) and absence (magenta) of taxol. Solid lines, best fits to a Gaussian distribution. Mean velocity (± standard error) and sample size (n) are indicated. The velocity distributions do not differ significantly from each other (P = 0.82, Student’s t-test).