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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Cytoskeleton (Hoboken). 2017 Jul 24;74(9):356–366. doi: 10.1002/cm.21386

Figure 3. The dissociation rate of a single kinesin does not differ significantly between GMPCPP and GDP microtubules (MTs).

Figure 3

Taxol (25 μM) was present in buffers during motility experiments for both MT types. (A) Cumulative probability distributions of the association time of single kinesins with GMPCPP MTs (n = 136) and GDP MTs (n = 138). Solid lines, best fits to 1-Ae−x/t. Mean association time (t ± standard error) is indicated. The two best-fit solid lines share the same average association time and thus overlap with each other. These distributions do not differ significantly from each other (P = 0.50, rank-sum test). (B) Dot plot of single-kinesin dissociation rate for each microtubule type, calculated as the reciprocal of the association time in (A). Horizontal bars indicate mean values and quartiles. These two distributions do not differ significantly from each other (P = 0.50, rank-sum test).