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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Vaccine. 2017 Nov 7;35(51):7174–7180. doi: 10.1016/j.vaccine.2017.10.078

Figure 2. Cellular immune responses after the immunization with AdC7OprF.RGD in mice with established P. aeruginosa respiratory infection.

Figure 2

C57BL/6 mice were immunized intranasally with either 1×1010 particle units of AdC7OprF.RGD, AdC7Null or PBS 4 days after the administration of P. aeruginosa embedded in agar beads. Two weeks after the immunization, the splenocytes were collected, cultured and stimulated with OprF protein for 48 h. A. IFN-γ and B. IL-4 levels were measured in the culture supernatants by ELISA. Data are presented as mean ± SEM of n=8 mice per group. * and ** denote significance of p < 0.05 and p < 0.01 respectively.