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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Eur J Med Chem. 2017 Oct 10;143:1261–1276. doi: 10.1016/j.ejmech.2017.10.026

Figure 5.

Figure 5

Compounds 27, 24 and Doxazosin docking with EphA2. EphA2 (PDB:3FL7) out membrane part was used to perform the docking study. The original identified Doxazosin binding site was used to fit the compounds. Compound 24 and Doxazosin share the similar binding mode, whereas compound 27 shows a different binding characteristic.