Table I.
Laterality | Metabolites | Sham | MCAO | MCAO + EA |
---|---|---|---|---|
Left | NAA/Cr | 1.44±0.29 | 1.08±0.25a | 1.31±0.28b |
Glu/Cr | 0.56±0.07 | 0.56±0.16 | 0.55±0.10 | |
Cho/Cr | 0.65±0.12 | 0.62±0.10 | 0.67±0.15 | |
Right | NAA/Cr | 1.39±0.11 | 1.37±0.13 | 1.37±0.20 |
Glu/Cr | 0.57±0.09 | 0.55±0.17 | 0.58±0.11 | |
Cho/Cr | 0.70±0.13 | 0.63±0.14 | 0.67±0.09 | |
Left/right | NAA/Cr | 0.95±0.10 | 0.76±0.12a | 0.84±0.20b |
Glu/Cr | 0.85±0.13 | 0.87±0.16 | 0.83±0.23 | |
Cho/Cr | 0.93±0.25 | 0.81±0.10a | 0.90±0.25 |
Metabolite ratios in the right and left HPC regions of the sham, MCAO and MCAO + EA groups, and left/right ratios in each group. Data are presented as mean ± standard deviation (n=12 per group).
P<0.05, MCAO vs. sham;
P<0.05, MCAO vs. MCAO + EA. HPC, hippocampus; NAA, N-acetylaspartate; Cr, creatine; Glu, glutamate; Cho, choline-containing compounds; MCAO, middle cerebral artery occlusion; EA, electroacupuncture.