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. 2017 Dec 8;41(2):946–954. doi: 10.3892/ijmm.2017.3314

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Characterization of hsa_circ_0067531 and hsa_circ_0057096 in HCC tissues. (A) Head-to-tail splicing was assayed by a qPCR reaction, with divergent primers and (B) Sanger sequencing. (C) hsa_circ_0067531 and (D) hsa_circ_0057096 expressions were examined in eight pairs of the HCC tissues and in the corresponding non-tumor tissues using qPCR. The expression of hsa_circ_0067531 in HCC tissues was significantly decreased compared with adjacent normal tissues (P=0.012), however there was no significant difference in hsa_circ_0057096 expression between adjacent normal tissues and HCC tissues. ^*P<0.05 vs. adjacent. HCC, hepatocellular carcinoma; qPCR, quantitative polymerase chain reaction.