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. 2017 Nov 2;2(21):e94929. doi: 10.1172/jci.insight.94929

Figure 9. Macrophage polarization and activation are influenced by Pla2g10 status.

Figure 9

(A) Concentrations of resident macrophages in lung tissue from WT and Pla2g10–/– mice were similar after saline and HDM challenge. The surface expression of (B) CD206/MR and (C) CD71/TfR on these resident macrophages was assessed to measure the extent of M2 polarization. (D) HDM-induced recruited macrophages in lung tissue were also evaluated by multicolor flow. In this recruited macrophage population, the surface expression of (E) CD206/MR and (F) CD71/TfR was also evaluated to determine M2 polarization. n = 4–5 mice/group. Mean ± SEM, 2-way ANOVA with uncorrected Fisher’s LSD.