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. 2017 Dec 21;2(24):e94500. doi: 10.1172/jci.insight.94500

Figure 5. T cell responses to PDK53 vaccination in pups born to PDK53-immune dams.

Figure 5

Pups born to PDK53-immune or naive dams were immunized with 105 PFU of PDK53 at 3 weeks of age and blood was collected 7 days later for analysis of T cell populations. (A) Proportions of total CD4+ and CD8+ T cells. Each data point represents 1 mouse; short lines represent medians and interquartile ranges. (B) Proportions of effector (CD44hiCD62Llo) CD4+ and CD8+ T cells. (C) Proportions of IFN-γ+ CD8+ T cells after in vitro stimulation with DENV2 NS4B99–107 peptide. Mann-Whitney test was performed. *P ≤ 0.05; **P ≤ 0.01; ns, P > 0.05. Data are representative of 2 independent experiments.