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GPCR-ome screening was conducted according to the PRESTO-Tango assays, as outlined in the Methods. W-15 and W-18 were screened at a final concentration of 1 μM, in quadruplicate for both sample and basal, and results are presented in fold of basal. Dopamine (D2) receptor with 100 nM quinpirole served as an assay control. A represents GPCRome screen of W-18. B represents GPCRome screen of W-15.
