Table 4. Significantly changing genes in EOC models following PAX8 knockdown.
| HeyA8 | IGROV1 | ||||
|---|---|---|---|---|---|
| Gene Name | Fold Change | P-value | Gene Name | Fold Change | P-value |
| Downregulated Genes | Downregulated Genes | ||||
| DCDC2 | -2.8 | 8.82E-07 | SPON1 | -13.4 | 3.50E-10 |
| SLC7A5 | -2.6 | 1.09E-03 | KRT24 | -12.0 | 4.32E-12 |
| CDH5 | -2.1 | 1.12E-05 | MMP7 | -6.8 | 4.77E-06 |
| FAM167A | -2.1 | 1.25E-05 | APBB1IP | -3.3 | 2.06E-07 |
| C8ORF13 | -2.0 | 2.25E-05 | LOC644612 | -3.3 | 5.00E-04 |
| H2AFY2 | -2.0 | 1.23E-03 | THY1 | -3.2 | 1.84E-08 |
| IL11 | -2.0 | 2.37E-04 | C1ORF85 | -3.1 | 8.82E-09 |
| C13ORF15 | -2.0 | 7.73E-09 | STK32B | -3.0 | 2.16E-05 |
| PAX8 | -1.9 | 4.57E-06 | SAMD5 | -3.0 | 4.90E-06 |
| SCD | -1.9 | 6.61E-06 | CYP4F11 | -2.8 | 5.45E-06 |
| Upregulated Genes | Upregulated Genes | ||||
| IL1B | 2.6 | 3.92E-05 | LOC149501 | 8.0 | 1.19E-09 |
| LOC644350 | 2.6 | 7.50E-07 | KRT18P13 | 8.2 | 2.23E-10 |
| SCG5 | 2.7 | 1.92E-06 | MGC42367 | 8.4 | 8.26E-10 |
| STC1 | 2.7 | 2.51E-05 | LOC399965 | 8.8 | 6.92E-11 |
| HNRPLL | 2.7 | 5.59E-11 | EMP1 | 9.1 | 3.39E-11 |
| IL8 | 3.3 | 3.18E-05 | ANKRD1 | 10.8 | 4.06E-09 |
| LPXN | 3.5 | 3.06E-07 | LOC644743 | 11.0 | 1.35E-11 |
| IL13RA2 | 3.9 | 4.50E-14 | KRT8 | 12.2 | 1.74E-11 |
| LOC728285 | 4.2 | 8.81E-09 | LOC647954 | 12.2 | 5.67E-12 |
| TGFBI | 6.2 | 5.51E-09 | CDH17 | 20.4 | 6.37E-10 |