Table 6. PAX8 putative enhancer regulatory targets.
| Gene Symbol | HeyA8 | IGROV1 | ||
|---|---|---|---|---|
| p-value | Fold change | p-value | Fold change | |
| ANKRD1 | 2.02E-03 | 1.57 | 4.06E-09 | 10.79 |
| VASN | 4.02E-07 | 1.74 | 5.38E-11 | 6.04 |
| IL1B | 3.92E-05 | 2.57 | 1.10E-04 | 1.26 |
| PAX8 | 4.57E-06 | -1.95 | 6.51E-08 | -2.35 |
| CLIC3 | 1.19E-04 | 1.25 | 1.58E-03 | 2.07 |
| HIST2H2AA3 | 8.41E-07 | 2.00 | 2.24E-06 | 1.73 |
| AJAP1 | 3.82E-10 | -1.94 | 2.17E-09 | -1.77 |
| SLC26A2 | 1.50E-03 | -1.29 | 2.51E-06 | -1.91 |
| HIST1H2BK | 2.20E-05 | 1.90 | 1.33E-05 | 1.85 |
| GCLM | 5.78E-06 | -1.33 | 3.94E-05 | -1.87 |
| HIST2H2AA4 | 1.79E-06 | 1.86 | 8.88E-07 | 1.56 |
| MXD4 | 3.62E-04 | 1.73 | 1.10E-04 | 1.35 |
| ELFN2 | 7.37E-05 | -1.50 | 7.67E-06 | -1.72 |
| RRAS2 | 6.42E-04 | -1.45 | 5.91E-08 | -1.69 |
| CTSL2 | 1.65E-04 | -1.41 | 6.56E-09 | -1.61 |
| SLC25A15 | 6.35E-07 | -1.59 | 4.85E-06 | -1.61 |
| HIST2H2AC | 1.35E-06 | 1.59 | 3.62E-04 | 1.50 |
| ATOX1 | 6.52E-05 | 1.26 | 8.64E-07 | 1.52 |
| CASP1 | 3.96E-08 | 1.52 | 5.99E-04 | 1.24 |
| S100A13 | 7.89E-06 | -1.51 | 2.82E-04 | -1.36 |
| EVI5L | 8.13E-06 | 1.26 | 9.11E-07 | 1.46 |
| CEP55 | 5.11E-05 | -1.45 | 2.16E-03 | -1.21 |
| UBA7 | 7.76E-05 | 1.44 | 7.35E-06 | 1.29 |
| CHAF1A | 5.70E-05 | -1.24 | 1.21E-04 | -1.43 |
| SKA3 | 9.17E-04 | -1.36 | 7.51E-04 | -1.41 |
| SH3BGRL3 | 5.28E-08 | 1.41 | 3.79E-04 | 1.23 |
| PTPRF | 8.77E-10 | 1.41 | 1.32E-05 | 1.35 |
| S100A6 | 5.02E-04 | 1.34 | 4.37E-05 | 1.41 |
| NRP1 | 4.26E-06 | 1.36 | 1.09E-05 | 1.39 |
| EHD2 | 4.79E-04 | 1.29 | 6.48E-04 | 1.39 |
| XPO4 | 2.85E-03 | -1.36 | 2.78E-05 | -1.37 |
| RHOC | 7.17E-07 | 1.37 | 1.26E-04 | 1.24 |
| KIAA1539 | 2.13E-07 | 1.29 | 4.36E-04 | 1.36 |
| JARID2 | 1.27E-03 | 1.28 | 8.05E-06 | 1.36 |
| CASP4 | 2.59E-03 | 1.21 | 3.46E-05 | 1.36 |
| TROAP | 1.02E-03 | -1.31 | 2.81E-03 | -1.36 |
| DUSP28 | 1.25E-03 | 1.31 | 7.97E-05 | 1.34 |
| SEPW1 | 6.62E-05 | 1.33 | 1.63E-03 | 1.30 |
| FEN1 | 9.88E-06 | -1.33 | 8.67E-05 | -1.23 |
| ACAA2 | 1.45E-03 | -1.21 | 5.36E-05 | -1.33 |
| MPHOSPH8 | 7.94E-04 | -1.30 | 4.22E-04 | -1.31 |
| POLR3K | 4.38E-04 | -1.27 | 1.83E-04 | -1.31 |
| FOXM1 | 2.30E-06 | -1.29 | 1.24E-04 | -1.26 |
| NUP210 | 2.99E-03 | -1.20 | 9.35E-05 | -1.29 |
| POLD1 | 7.56E-08 | -1.28 | 1.92E-03 | -1.23 |
| CHTF18 | 3.49E-04 | -1.26 | 2.28E-03 | -1.28 |
| CDCA5 | 1.41E-03 | -1.24 | 6.80E-05 | -1.28 |
| DSCC1 | 2.08E-05 | -1.28 | 4.92E-05 | -1.28 |
| FRAT2 | 8.96E-04 | -1.26 | 1.82E-03 | -1.20 |
| GPRIN1 | 1.16E-04 | -1.25 | 3.79E-04 | -1.25 |
| ZNF259 | 3.22E-04 | -1.24 | 7.71E-05 | -1.25 |
| FANCG | 1.99E-03 | -1.21 | 1.79E-04 | -1.25 |
| OIP5 | 1.46E-04 | -1.22 | 2.65E-03 | -1.25 |
| M6PRBP1 | 1.99E-05 | 1.22 | 1.95E-03 | 1.20 |
Shown are the DEGs changing in the same direction when PAX8 is knocked down in HeyA8 and IGROV1, sorted by absolute fold change.