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. 2017 Nov 26;8(65):108418–108429. doi: 10.18632/oncotarget.22664

Figure 3. CysLT1 receptor antagonists alleviate pathogenesis of CIA.

Figure 3

CIA was induced in male DBA mice by immunization with chicken type II collagen. Drugs (montelukast 30mg/kg/d) were given once daily via i.p. injection from day 1 post booster immunization till the end of the study and clinical scores were recorded. Control groups were treated with 0.9% saline injections. Data are presented as mean ± SEM (n=6) and are representative of three independent experiments. *p < 0.05, **p < 0.01, versus vehicle control (Mann-Whitney test).