Table 3. Allele frequencies in cases and controls and odds ratio estimates for ONFH.
SNP ID | Gene | Position | Alleles A/B | MAF | pa value for HWE | ORs | 95% CI | pb | ||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | |||||||||
rs639752 | MMP3 | 11q22.2 | C/A | 0.32 | 0.35 | 0.116 | 0.88 | 0.74 | 1.06 | 0.177 |
rs650108 | MMP3 | 11q22.2 | G/A | 0.39 | 0.44 | 0.147 | 0.84 | 0.70 | 0.99 | 0.040* |
rs520540 | MMP3 | 11q22.2 | A/G | 0.32 | 0.35 | 0.116 | 0.88 | 0.74 | 1.06 | 0.177 |
rs646910 | MMP3 | 11q22.2 | A/T | 0.07 | 0.09 | 1 | 0.82 | 0.60 | 1.13 | 0.224 |
rs602128 | MMP3 | 11q22.2 | A/G | 0.32 | 0.34 | 0.235 | 0.90 | 0.75 | 1.07 | 0.234 |
rs679620 | MMP3 | 11q22.2 | T/C | 0.32 | 0.35 | 0.202 | 0.88 | 0.74 | 1.05 | 0.156 |
rs678815 | MMP3 | 11q22.2 | G/C | 0.32 | 0.35 | 0.141 | 0.88 | 0.74 | 1.05 | 0.165 |
rs522616 | MMP3 | 11q22.2 | C/T | 0.40 | 0.35 | 0.923 | 1.20 | 1.00 | 1.42 | 0.044* |
SNP single nucleotide polymorphism, HWE Hardy-Weinberg equilibrium, OR odds ratio, 95% CI 95% confidence interval, MAF minor allele frequency.
* p ≤ 0.05 indicates statistical significance.
a p was calculated by exact test.
bp was calculated by Pearson Chi-squared test.