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. 2017 Nov 20;8(65):109027–109042. doi: 10.18632/oncotarget.22561

Figure 9. The mRNA expression levels of IgA class switching markers, thymic stromal lymphopoietin (TSLP), TSLP receptor (TSLPR), activation-induced cytidine deaminase (AID) and transforming growth factor-β1 (TGF-β1) were decreased in tonsillar GCs of IgAN patients with Tripterygium Wilfordii treatment.

Figure 9

RT-PCR was used to measure mRNAs encoding β-actin, TSLP, TSLPR, AID, TGF-β1, BAFF, APRIL, germline Cα (Iα-Cα), and switch circle (Iα-Cμ) in tonsillar GCs of IgAN patients and non-IgAN patients with chronic tonsillitis. TSLP, TSLPR, AID, and TGF-β1 mRNA levels were determined by real-time PCR and normalized to β-actin mRNA levels in tonsillar GCs from IgAN patients with Tripterygium Wilfordii treatment (n = 20), IgAN patients without treatment (n = 20) and non-IgAN patients with chronic tonsillitis (n = 20). Error bars indicate SEMs. *, P < 0.01 (Mann-Whitney U test).