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. 2017 Nov 17;8(65):109107–109119. doi: 10.18632/oncotarget.22619

Table 2. Primary information for TCF7L2 rs7903146C>T, rs290481 T>C, LEP rs7799039 A>G, rs2167270 G>A and LEPR rs1137100 G>A, rs1137101 G>A and rs6588147 G>A polymorphisms.

Genotyped SNPs Chromosome Chr Pos (NCBI Build 37) Region MAFa for Chinese in database MAF in our controls (n = 1, 496) P value for HWEb test in our controls Genotyping method Genotyping value (%)
TCF7L2 rs7903146 C>T 10 114758349 Intron 4 0.026 0.031 0.733 SNPscan 99.50
TCF7L2 rs290481 T>C 10 114923825 Intron 13 0.405 0.387 0.097 SNPscan 99.45
LEP rs7799039 A>G 7 127878783 Promoter 0.201 0.266 0.543 SNPscan 99.50
LEP rs2167270 G>A 7 127881349 5’ UTR 0.175 0.222 0.324 SNPscan 99.40
LEPR rs1137100 G>A 1 66036441 Exon 4 0.169 0.160 0.316 SNPscan 99.50
LEPR rs1137101 G>A 1 66058513 Exon 6 0.111 0.122 0.763 SNPscan 99.50
LEPR rs6588147 G>A 1 65935494 Intron 2 0.150 0.150 0.260 SNPscan 99.50

a MAF: minor allele frequency.

b HWE: Hardy–Weinberg equilibrium.