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. 2017 Nov 24;8(65):109151–109160. doi: 10.18632/oncotarget.22642

Figure 1. Treatment with 5H4 mAb reduced CD8+CD122+ T cell population.

Figure 1

Naïve B6 non-tumor bearing mice were injected i.p. with 100 ug of 5H4 anti-CD122 mAb or with the isotype (rat IgG2a) control. Three days after injection, splenocytes were analyzed for CD8+CD122+ T cells by flow cytometry. (A-B) Flow plot analysis and representative data showing the percentages of CD8+CD122+ T cells and the MFI of CD122 on CD8+CD122+ T cells in total splenic lymphocytes. Isotype indicates CD8+ splenocytes stained with the isotype control antibody for CD122 staining. Results are representative of 2 independent experiments. ****P<0.0001. Errors bars indicate SEM of n = 5/group.