Table 1. Relationship between XRCC1 staining and clinicopathological characteristics of the individuals in two cohorts of ccRCC patients.
| Variables | Training cohort (75 cases) | Validation cohort (300 cases) | ||||
|---|---|---|---|---|---|---|
| Low (%) | High (%) | P * | Low (%) | High (%) | P * | |
| Age | ||||||
| ≤56 years | 17 (47.2) | 19 (52.8) | 0.216 | 105 (45.3) | 38 (26.6) | 1.000 |
| >56 years | 10 (41.0) | 23 (59.0) | 116 (73.9) | 41 (26.1) | ||
| Gender | ||||||
| Male | 21 (42.0) | 29 (58.0) | 0.201 | 143 (72.2) | 55 (27.8) | 0.490 |
| Female | 6 (24.0) | 19 (76.0) | 78 (76.5) | 24 (23.5) | ||
| Tumor size | ||||||
| ≤7 cm | 9 (42.9) | 12 (57.1) | 0.056 | 169 (72.5) | 64 (27.5) | 0.436 |
| >7 cm | 18 (33.3) | 36 (66.7) | 52 (77.6) | 15 (22.4) | ||
| pT status | ||||||
| pT1- pT2 | 21 (33.9) | 41 (66.1) | 0.527 | 180 (73.8) | 64 (26.2) | 1.000 |
| pT3 -pT4 | 6 (46.2) | 7 (53.9) | 41 (73.2) | 11 (26.8) | ||
| pN status | ||||||
| pN0 | 23 (32.4) | 48 (67.6) | 0.031 | 201 (73.3) | 73 (26.7) | 0.042 |
| pN1 –pN3 | 4 (100.0) | 0 (0.0) | 20 (90.9) | 2 (9.1) | ||
| TNM stage | ||||||
| I-II | 17 (29.8) | 40 (70.2) | 0.056 | 164 (75.9) | 52 (24.1) | 0.288 |
| III-IV | 10 (55.6) | 8 (44.4) | 35 (68.6) | 16 (31.4) | ||
* Two sided Fisher’s exact tests.
Some cases were not available for the information in the validation cohort.