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. 2017 Nov 25;8(65):109393–109401. doi: 10.18632/oncotarget.22682

Table 3. Comparison of oral rinse results with tumor status: total oropharynx and subsite-specific results shown.

Total oropharynx Tumor p16 status Total
Positive Negative
Oral rinse Results of HPV PCR HPV16 or HPV18 Positive 32 2 34
HPV16 or HPV18 Negative 9 2 11
Total 41 4 45
Sensitivity = 78%, Specificity = 50%, PPV = 94%, and NPV = 18%.
Tonsil Tumor p16 status Total
Positive Negative
Oral rinse Results of HPV PCR HPV16 or HPV18 Positive 19 0 19
HPV16 or HPV18 Negative 3 0 3
Total 22 0 22
Sensitivity = 86%, Specificity = not evaluable, PPV = 100%, and NPV = not evaluable.
Base of tongue Tumor p16 status Total
Positive Negative
Oral rinse Results of HPV PCR HPV16 or HPV18 Positive 13 2 15
HPV16 or HPV18 Negative 6 2 8
Total 19 4 23
Sensitivity = 68%, Specificity = 50%, PPV = 87%, and NPV = 25%.