Table 3. Comparison of oral rinse results with tumor status: total oropharynx and subsite-specific results shown.
Total oropharynx | Tumor p16 status | Total | ||
---|---|---|---|---|
Positive | Negative | |||
Oral rinse Results of HPV PCR | HPV16 or HPV18 Positive | 32 | 2 | 34 |
HPV16 or HPV18 Negative | 9 | 2 | 11 | |
Total | 41 | 4 | 45 | |
Sensitivity = 78%, Specificity = 50%, PPV = 94%, and NPV = 18%. |
Tonsil | Tumor p16 status | Total | ||
---|---|---|---|---|
Positive | Negative | |||
Oral rinse Results of HPV PCR | HPV16 or HPV18 Positive | 19 | 0 | 19 |
HPV16 or HPV18 Negative | 3 | 0 | 3 | |
Total | 22 | 0 | 22 | |
Sensitivity = 86%, Specificity = not evaluable, PPV = 100%, and NPV = not evaluable. |
Base of tongue | Tumor p16 status | Total | ||
---|---|---|---|---|
Positive | Negative | |||
Oral rinse Results of HPV PCR | HPV16 or HPV18 Positive | 13 | 2 | 15 |
HPV16 or HPV18 Negative | 6 | 2 | 8 | |
Total | 19 | 4 | 23 | |
Sensitivity = 68%, Specificity = 50%, PPV = 87%, and NPV = 25%. |