Table 1. Baseline characteristics of patients with CAD.
| Baseline characteristics | Total | Acute coronary syndrome | Stable CAD | P value |
|---|---|---|---|---|
| Patients, n | 1285 | 759 | 526 | |
| Age, y | 64.8 (10.8) | 64.1 (11.2) | 65.8 (10.2) | 0.05 |
| Female, % | 33.5 | 29.0 | 39.9 | <0.001 |
| Body mass index, kg/m2 | 23.9 (3.32) | 23.8 (3.32) | 24.0 (3.32) | 0.33 |
| Systolic blood pressure, mm Hg | 134 (23) | 134 (23) | 136 (23) | 0.38 |
| Diastolic blood pressure, mm Hg | 77 (13) | 76 (13) | 77 (12) | 0.54 |
| Triglyceride, mmol/L | 1.85 (1.28) | 1.87 (1.20) | 1.82 (1.38) | 0.66 |
| Low-density lipoprotein cholesterol, mmol/L | 2.98 (0.98) | 3.02 (1.01) | 2.94 (0.94) | 0.06 |
| Hemoglobin, g/L | 130(20.4) | 130(21.6) | 129(18.3) | 0.83 |
| Iron, μmol/L | 13.0 (6.5) | 12.6 (6.7) | 13.7 (6.2) | <0.001 |
| Unsaturated iron-binding capacity, μmol/L | 28.2 (12.8) | 28.3 (14.0) | 28.2 (10.7) | 0.84 |
| Transferrin saturation, % | 33.5 (15.7) | 32.8 (15.9) | 34.4 (15.4) | 0.08 |
| Soluble transferrin receptor, mg/L | 3.18 (2.04) | 3.15 (2.21) | 3.21 (1.77) | 0.80 |
| C-reactive protein, mg/L | 3.80 (1.00-13.9) | 6.50 (1.55-18.8) | 1.92 (0.72-6.16) | <0.001 |
| Interleukin-6, pg/mL | 1.64 (0.66-3.50) | 1.78 (0.80-4.01) | 1.48 (0.56-2.96) | <0.001 |
| Ferritin, ng/mL | 285 (168-436) | 317 (198-486) | 229 (146-367) | <0.001 |
| Hepcidin, ng/mL | 24.6(14.1-39.7) | 27.1(17.2-42.6) | 21.3 (11.2-34.5) | <0.001 |
| Duration of CAD, y | ||||
| First diagnosed CAD (n=753) | -- | -- | -- | -- |
| History of CAD (n=532) | 3.80 (1.17-9.01) | 3.44 (1.00-8.79) | 4.00 (1.44-9.49) | 0.08 |
| Years of education, % | 0.77 | |||
| ≤9 | 60.5 | 61.3 | 59.2 | |
| 10-12 | 21.6 | 20.9 | 22.7 | |
| ≥13 | 17.9 | 17.8 | 18.1 | |
| Leisure-time physical activities, % | 0.09 | |||
| None | 32.3 | 34.9 | 28.5 | |
| <30 minutes/day | 22.2 | 20.8 | 24.2 | |
| ≥30 minutes/day | 45.5 | 44.3 | 47.3 | |
| Smoking, % | <0.001 | |||
| Never | 60.5 | 55.7 | 67.5 | |
| Past | 9.9 | 8.5 | 11.9 | |
| Current | 29.6 | 35.8 | 20.6 | |
| Alcohol use, % | 0.62 | |||
| Never | 77.7 | 78.4 | 76.8 | |
| Past | 7.6 | 7.0 | 8.6 | |
| Current | 14.7 | 14.6 | 14.7 | |
| Coronary artery stenosis degree of Coronary Angiography, % | <0.001 | |||
| 50-74.9% | 24.3 | 14.0 | 47.5 | |
| ≥75% | 75.7 | 86.0 | 52.5 | |
| Prevalence of hypertension, % | 92.6 | 93.8 | 90.9 | 0.05 |
| Prevalence of diabetes, % | 43.1 | 46.8 | 37.9 | 0.002 |
| Uses of medications, % | ||||
| Antiplatelet/anticoagulant medication, % | 88.2 | 90.6 | 84.6 | 0.001 |
| Antihypertensive medication, % | 87.9 | 89.3 | 85.9 | 0.06 |
| Lipid-lowering medication, % | 81.9 | 84.8 | 77.6 | 0.001 |
| Glucose-lowering medication, % | 25.9 | 26.7 | 24.7 | 0.26 |
Continuous data are reported as M (SD) if normally distributed and median (25th, 75th percentile) if non-normally distributed, categorical data are reported as percentages. All continuous variables are adjusted for age and gender, except for age (adjusted for gender only).
CAD, coronary artery disease.