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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Mol Cancer Res. 2017 Sep 28;16(1):162–172. doi: 10.1158/1541-7786.MCR-17-0221

Figure 1. IL-1β expression and secretion increases with CD133 expression.

Figure 1

(a) Positive correlation of CD133 and IL-1β gene expression in several established pancreatic cancer cell lines p<0.0001 (linear regression). (b) IL-1β gene expression in the CD133− and CD133+ sorted populations of KPC tumor cells * p<0.05 (unpaired t-test). (c) Increased IL-1β gene expression upon overexpression of CD133 in MIA PaCa-2 cells *p<0.05 as determined by analysis of variance (ANOVA). (d) Increased IL-1β secretion upon overexpression of CD133 in MIA PaCa-2 cells *p<0.05 as determined by analysis of variance (ANOVA). Each bar is representative of three or more independent experiments; error bars are represented in s.e.m.